Posted by Mushroom supplements are no longer niche wellness products that most of us would have never touched, even with a yardstick; they are almost mainstream health staples, thanks to their many potential benefits, from vitality to cognition and immunity. Don’t take my word for it, just yet, the demand for functional mushroom supplements like Cordyceps, Reishi, and Lion’s mane is soaring, as evidenced by the 75.8% increase in sales in 2023. The market is expected to reach $6 billion by 2030.
Here is a detailed breakdown of the side effects of mushroom supplements, how to use them safely, and advanced microdosing options, such as the Mindless mushroom tablets.
Quick Overview of Popular Mushroom Supplements
But before we discuss the side effects, let’s look at the benefits of different functional mushroom supplements.
- Lion’s Mane: Boosts brain function, nerve regeneration, and cognition
- Reishi: Support immune system, reduces stress, and is rich in antioxidants
- Cordyceps: Supports energy, stamina, and respiratory health
- Chaga: Rich in antioxidants and supports cellular health
- Turkey Tail: Supports immunity and is often used alongside chemotherapy
- Shiitake: Supports immunity, heart health, and overall wellness
- Maitake: Regulates blood sugar and immune function
Like other natural botanicals like kratom and kava, these functional mushrooms are generally safe when used in moderation. The side effects depend on individual sensitivity, dosage, and quality of the supplement. Sadly, some supplements on the market are not properly lab-tested or standardized, as recently reported by the FDA.
How Do Mushroom Supplements Work
Herbal supplements contain active compounds that interact with the body’s systems, such as the nervous system, to produce beneficial effects. Mushroom supplements contain triterpenes and beta-glucans, which support cognitive function and immunity.
There is always a risk of side effects even when used in small amounts. But advanced mushroom supplements like the Mindless Mushroom tablets from Real Botanicals are designed for microdosing, NOT intensity.
Are Mushroom Supplements Safe
Yes, quality mushroom supplements are generally safe, but some people report mild to moderate reactions after using them. These include;
- Digestion issues: Diarrhea, bloating, nausea, and mild stomach cramps
- Allergic reactions: Itching, rashes, and respiratory irritation
- Interaction with medications: You should not use mushroom supplements if you are on immunosuppressants and blood thinners
- Fatigue or dizziness: This is often reported after using high doses of Cordyceps or Reishi
You can reduce the effects by starting with a low dose and increasing gradually. Safety and quality should be your top priority when shopping for mushroom supplements.
We insist that you buy from reputable brands and, if possible, go for microdosing tablets. Check out this guide on how to microdose mushrooms to avoid most of the side effects and still get the full benefits.
Side Effects By Mushroom Supplement Type
| Mushroom supplement | Common side effects | How Best to Use |
| Lion’s Mane | Skin irritation and mild stomach upset | Best used at 1g per day for up to 16 weeks, then take a break |
| Reishi | Dizziness, nausea, rashes, dry mouth, stomach upset | Avoid long-term continuous use beyond 16 weeks without breaks to help your body reset to baseline |
| Cordyceps | Constipation, mild stomach cramps, and diarrhea | Typical dosage: 3 to 6 grams per day; they are generally well-tolerated over long periods. |
| Chaga | Interaction with blood-thinning medications and kidney stones | Not recommended for people with kidney disease or on anticoagulant medications. should consult a doctor first. |
| Turkey Tail | Vomiting, nausea, mild changes to liver enzymes | Often used in adjunct therapy during chemotherapy. Liver health should be closely monitored |
| Shiitake | Stomach discomfort, skin rash, and breathing issues | Powdered extracts can cause mild reactions in sensitive individuals. It’s generally safe when cooked |
| Maitake | Mild digestive upset and low blood sugar | Continuously monitor your blood sugar levels if you’re diabetic |
How To Minimize Side Effects of Mushroom Supplements
What if I told you there was a way to reduce the side effects of mushroom supplements? That’s right, here are five tips on how to achieve this goal.
- Start low and go slow: Begin with a low dose and increase gradually as you notice effects.
- Check Ingredients: Before buying, read the label and description. Ideally, you should avoid supplements with unnecessary fillers, additives, or mycelium on-grain powders that are known to irritate the gut.
- Take Breaks: Regular breaks will help reset your tolerance and nervous system. Trying different supplements, such as Lion’s Mane and Reishi, can help prevent tolerance buildup and adverse effects.
- Talk to your Doctor: Consult your doctor if you’re on medications or have a history of substance abuse.
- Go for Precision Dosed Products: Microdosed tablets like Mindless tablets support a safe and controlled dosing approach.
Insist on mushroom supplements that have undergone third-party lab testing for potency and contaminants. Reputable brands like Real Botanicals disclose this information and can cushion you from these side effects.
So, Should I Buy Mushroom Supplements?
Mushroom supplements can offer a range of benefits, from immune modulation to cognitive support. But they are not free from side effects, just like other herbal supplements in the market.
Our final recommendation is that you choose high-quality, lab-tested functional mushroom tablets. Start with a low dose and pay attention to how your body responds.