Posted by Kratom is not as dangerous as most blogs and state health regulators purport. The side effects, like sedation and dependence, are caused by users not sticking to the recommended dosage or buying from unscrupulous vendors who don’t abide by GMP standards.
You should only buy kratom from a vendor who has a clean reputation, offers a Certificate of Analysis before purchase, and whose products are tested and verified by an independent third-party lab.
Back to your question, can I mix kratom and alcohol? NO, and I would strongly advise you to avoid this combo at all costs. Most people drink alcohol to relax and socialize. I can see why combining kratom with another product that is widely used for “emotional support and socializing tool” somehow seems reasonable.
Key Takeaways
- Mixing kratom with alcohol can increase the risk of drowsiness, dizziness, impaired coordination, nausea, and other serious outcomes.
- CDC data found that multiple-substance kratom exposures had higher hospitalization and serious-outcome rates than single-substance exposures.
- Acend provides 160mg of full-spectrum kratom extract per tablet, with a recommended 40mg serving and a 160mg maximum within 24 hours.
- Oxonol contains MGM-15 and mitragynine, while Pseudo contains 50mg of mitragynine pseudoindoxyl per tablet and offers different effects and serving sizes.
- Oxonol, Pseudo, and Acend are concentrated extracts for experienced users, and you should never combine them with alcohol, sedatives, opioids, or other substances that affect the central nervous system.
What Are the Effects of Combining Kratom With Alcohol
Truth is, combining kratom and alcohol is dangerous and will aggravate the effects of each. They both affect the central nervous system, and so combining them makes their effects harder to predict.
Here is scientific evidence of the effects of kratom with alcohol.
- Drowsiness and lethargy: Kratom can cause drowsiness when used in high doses, and because alcohol is a depressant, combining them increases the risk of sedation.
- Impaired coordination and dizziness: Both kratom and alcohol affect the nervous system. Using them together can potentially result in impaired judgment, poor coordination, and loss of balance.
- Nausea and vomiting: The National Capital Poison Center lists nausea and vomiting as some of the common effects of kratom. Alcohol can cause gastrointestinal issues, which could aggravate the issue.
- More severe outcomes in multiple-substance exposures: According to recent data from the CDC, kratom exposures involving multiple substances had higher hospitalization and serious-outcome rates than single-substance exposures.
Concisely, the available scientific findings do not establish a predictable kratom-alcohol dose response relationship, but we cannot ignore the fact that serious outcomes and deaths have occurred in multiple-substance kratom exposures, and ethanol was involved in 19% of kratom-associated deaths in the CDC’s 2015 to 2025 dataset.
This does NOT prove that alcohol caused those deaths or that kratom and alcohol alone caused them. For example, one of the reports we found states that among 233 kratom-associated deaths, 79% involved multiple substances, and ethanol appeared in 19% of those deaths.
If your goal is to relax, socialize, or stay focused without drinking alcohol, you do not need to combine alcohol with a kratom product to achieve that goal. The safer approach is to avoid mixing the two entirely and learn how each affects you on its own.
Even we the recent Notices of Intent from the DEA to ban concentrated 7-OH products, there are three products from Real Botanicals that you can still buy before August 5th.
Let’s shift gears and look at these 7-OH alternatives and how they can help you relax, unwind, and socialize without drinking alcohol.
Acend: A Full-Spectrum Kratom Extract
Acend is one of the 7-OH alternatives that is not affected by the federal ban, meaning it will still be available after the ban takes effect. Using ChromaPure technology, the Real Botanicals team of chemists extracts mitragynine and other naturally occurring kratom compounds and packages them in tablet form.
Each Acend tablet contains 160mg of fermented full-spectrum Mitragyna speciosa extract. It has a splittable design that allows users to split it into 4 equal servings, each delivering 40mg.
The effects kick in within 20-45 minutes, but we reckon that the full experience may take longer. To avoid overshooting, we recommend waiting for atleast 90 minutes before redosing, and you should not exceed one full table in a 24-hour window.
What are the Effects of Acend tablets?
Despite being the new kid on the block, Acend is already gaining ground and giving brands a run for their money. Some of the reported effects from customers are:
- Calm, grounded focus
- Mood lift without overstimulation
- Physical ease
- Mental clarity
- Steady energy
Note that individual responses vary, and Acend is intended for experienced kratom users.
Oxonol: MGM-15 and Mitragynine
Oxonol is another proprietary 7-OH alternative from Real Botanicals, containing MGM-15 and mitragynine. The product comes in 30mg and 60mg tablet formats.
The recommended serving depends on the tablet strength:
- 30mg tablet: Half a tablet provides 15mg
- 60mg tablet: One-quarter of a tablet provides 7.5mg
Like Acend, the effects are not instant. Wait for 30 to 45 minutes before considering redosing to avoid overstimulation. Remember, this is a highly concentrated kratom extract meant for experienced users. Also, don’t use more than two servings of the 30mg format or four servings of the 60mg format within 24 hours.
What Are The Effects of Oxonol?
We spoke to more than 100 customers who have tried Oxonol. The most common effects are;
- Mental quiet
- Smooth focus
- Mood support
- Deep relaxation
- Longer-lasting effects
Because Oxonol contains MGM-15, its federal status will change if the DEA’s temporary scheduling order takes effect.
Pseudo: Mitragynine Pseudoindoxyl
If you have used kratom extracts before and want some that feel close to pure 7-OH products like the 7-hydro tablets, go for Pseudo tablets. Pseudo is a concentrated kratom extract that contains 50mg of mitragynine pseudoindoxyl.
Compared to the 7-OH products, the Pseudo profile is different, and most experienced users say it’s more relaxing and grounding, with effects that last longer. Each tablet is scored and designed to split for easier serving control. The recommended serving is one-quarter of a tablet, which provides 12mg of mitragynine pseudoindoxyl.
What Are The Effects of Pseudo
Real Botanicals positions Pseudo as its strongest 7-OH alternative, and, like Acend and Oxonol, the brand designed it for experienced users. The effects include:
- Deep relaxation
- Long-lasting physical ease
- A heavier yet more settled feeling
- A more grounded experience
The DEA has specifically named mitragynine pseudoindoxyl in its temporary scheduling action. If the order takes effect, products containing this alkaloid will face federal restrictions.
So, Can I Mix Kratom and Alcohol?
NO. We have clearly explained the effects of this combination and why you should never do it. In fact, you don’t need to, thanks to the high-quality 7-OH alternatives and other kratom products offered by Real Botanicals.
If you choose to use a kratom extract, make sure you follow the serving instructions and do not mix it with alcohol, sedatives, opioids, or other substances that can affect the central nervous system.
More importantly, check federal and state laws before buying or possessing any kratom extract after the DEA’s temporary scheduling actions take effect.
Take advantage of the 20% off on Oxonol, Pseudo and Acend to stock up! Offer runs until August 5th.